Pulses longer than the thermal relaxation time of the hair shaft allow heat conduction and better damage of follicular stem cells. Epidermal cooling works far better with pulses longer than about 10 ms, delivered through a cold medium e.
Thus, the combination of cooling and long near-infrared laser pulses allows safe and effective pigmented hair removal in all skin types.
In contrast, epidermal protection from short pulses is best with dynamic pre-cooling e. A major challenge for the future of photothermal laser treatments is to develop ways of treating non-pigmented skin "targets". New uses for lasers are emerging. Diagnostic laser imaging and spectroscopy will soon emerge in dermatology. A near-infrared laser confocal microscope provides histology-like images of human skin. Imaging is painless and takes only a few minutes.
Lesions including melanoma, basal cell and squamous cell carcinoma, microvascular and inflammatory lesions, dermatophytes, verrucae, etc, have distinct appearances. However, sensitivity and specificity of laser-based diagnostic imaging has not yet been compared with histopathology. Laser phototherapy is also emerging in dermatology. The nm excimer laser has recently been shown to clear psoriasis faster than conventional phototherapy.
Scalp psoriasis may soon be treated by fiber-optic delivery of this UV laser. The variety and utility of lasers in dermatology will probably continue to grow.
Full text links Read article at publisher's site DOI : References Articles referenced by this article 25 Selective photothermolysis: precise microsurgery by selective absorption of pulsed radiation. Microvasculature can be selectively damaged using dye lasers: a basic theory and experimental evidence in human skin. Tunable dye laser nm treatment of port wine stains.
The effect of temperature and other factors on selective microvascular damage caused by pulsed dye laser. Treatment of children with port-wine stains using the flashlamp-pulsed tunable dye laser. Effect of dye laser pulse duration on selective cutaneous vascular injury. Thermal relaxation of port-wine stain vessels probed in vivo: the need for millisecond laser pulse treatment. Treatment of leg telangiectasia using a long-pulse dye laser at nm.
The optics of human skin. Laser therapy of spider leg veins: clinical evaluation of a new long pulsed alexandrite laser. Show 10 more references 10 of Smart citations by scite. The number of the statements may be higher than the number of citations provided by EuropePMC if one paper cites another multiple times or lower if scite has not yet processed some of the citing articles. Explore citation contexts and check if this article has been supported or disputed.
Lasers and ancillary treatments for scar management Part 2: Keloid, hypertrophic, pigmented and acne scars. Laser-induced capillary leakage for blood biomarker detection and vaccine delivery via the skin. Similar Articles To arrive at the top five similar articles we use a word-weighted algorithm to compare words from the Title and Abstract of each citation.
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Annotations submission service. Developers Developer resources. API case studies. SOAP web service. Annotations API. OAI service. Bulk downloads. In general, the ideal pulse duration is about equal to the thermal relaxation time for pigmented targets.
However, sometimes the actual target is not pigmented and is at some distance from a pigmented structure. For example the follicular stem cells, which are not pigmented, line the outer root sheath far away from the pigmented hair shaft.
These cells appear to be an important target for permanent hair destruction. Pulses longer than the thermal relaxation time of the hair shaft allow heat conduction and better damage of follicular stem cells. Epidermal cooling works far better with pulses longer than about 10 ms, delivered through a cold medium e.
Thus, the combination of cooling and long near-infrared laser pulses allows safe and effective pigmented hair removal in all skin types. In contrast, epidermal protection from short pulses is best with dynamic pre-cooling e. A major challenge for the future of photothermal laser treatments is to develop ways of treating non-pigmented skin "targets". New uses for lasers are emerging. Diagnostic laser imaging and spectroscopy will soon emerge in dermatology.
A near-infrared laser confocal microscope provides histology-like images of human skin.
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